Nardil has been shown to be very effective as a treatment for social anxiety in many research studies. You will see links to some of the more important studies below.
An important personality in this regard is Dr. Michael R. Liebowitz. He is a psychiatrist at Columbia University and the founding father of the highly respected Anxiety Disorders Clinic associated with New York State Psychiatric Institute. We can thank him for his research and publications in the 1980's which gave prominence and recognition to the relatively unknown at the time condition of Social Anxiety Disorder (SAD). His social anxiety test is one of the most widely used tools to measure level of social anxiety in clinical settings and for self assessments. You can view the test on the Social Anxiety Test page on this website.
Study 1: Several effective treatments for social phobia are now available, notably cognitive behavioural therapy and some antidepressant medications. Controlled trials indicate that 25-45% of patients fail to respond to the initial treatment... Phenelzine is effective in social phobia, and no treatment has been shown to be superior to phenelzine. Hence, phenelzine is a reasonable option for patients unresponsive to other treatments.
Nord, Phenelzine efficacy in refractory social anxiety disorder: a case series., J Psychiatry 2003;57(4):313-5. Access here.
Study 2: The medications with largest effect sizes were phenelzine (BRAND NAME: NARDIL) [effect size, 1.02; 95% Confidence Interval (CI), 0.52-1.52], clonazepam (effect size, 0.97; 95% CI, 0.49-1.45), gabapentin (effect size, 0.78; 95% CI, 0.29-1.27), brofaromine (effect size, 0.66; 95% CI, 0.38-0.94), and the selective serotonin reuptake inhibitors (SSRIs; effect size, 0.65; 95% CI, 0.50-0.81). ...
Pharmacological treatment of social anxiety disorder: a meta-analysis. Blanco C, Schneier FR, Schmidt A, Blanco-Jerez CR, Marshall RD, Sanchez-Lacay A, Liebowitz MR. Access here.
Study 3: Nineteen double-blind placebo-controlled studies on the treatment of Social Anxiety Disorder (Social Phobia) are reviewed. Initial trials yielded a high degree of efficacy for phenelzine (Brand Name: Nardil), a large difference between drug and placebo and a low rate of placebo response.
A review of 19 double-blind placebo-controlled studies in social anxiety disorder (social phobia). R. Visconde de Piraja Access here.
An important personality in this regard is Dr. Michael R. Liebowitz. He is a psychiatrist at Columbia University and the founding father of the highly respected Anxiety Disorders Clinic associated with New York State Psychiatric Institute. We can thank him for his research and publications in the 1980's which gave prominence and recognition to the relatively unknown at the time condition of Social Anxiety Disorder (SAD). His social anxiety test is one of the most widely used tools to measure level of social anxiety in clinical settings and for self assessments. You can view the test on the Social Anxiety Test page on this website.
Study 1: Several effective treatments for social phobia are now available, notably cognitive behavioural therapy and some antidepressant medications. Controlled trials indicate that 25-45% of patients fail to respond to the initial treatment... Phenelzine is effective in social phobia, and no treatment has been shown to be superior to phenelzine. Hence, phenelzine is a reasonable option for patients unresponsive to other treatments.
Nord, Phenelzine efficacy in refractory social anxiety disorder: a case series., J Psychiatry 2003;57(4):313-5. Access here.
Study 2: The medications with largest effect sizes were phenelzine (BRAND NAME: NARDIL) [effect size, 1.02; 95% Confidence Interval (CI), 0.52-1.52], clonazepam (effect size, 0.97; 95% CI, 0.49-1.45), gabapentin (effect size, 0.78; 95% CI, 0.29-1.27), brofaromine (effect size, 0.66; 95% CI, 0.38-0.94), and the selective serotonin reuptake inhibitors (SSRIs; effect size, 0.65; 95% CI, 0.50-0.81). ...
Pharmacological treatment of social anxiety disorder: a meta-analysis. Blanco C, Schneier FR, Schmidt A, Blanco-Jerez CR, Marshall RD, Sanchez-Lacay A, Liebowitz MR. Access here.
Study 3: Nineteen double-blind placebo-controlled studies on the treatment of Social Anxiety Disorder (Social Phobia) are reviewed. Initial trials yielded a high degree of efficacy for phenelzine (Brand Name: Nardil), a large difference between drug and placebo and a low rate of placebo response.
A review of 19 double-blind placebo-controlled studies in social anxiety disorder (social phobia). R. Visconde de Piraja Access here.